A molecular dynamics simulation study decodes the Zika virus NS5 methyltransferase bound to SAH and RNA analogue

Since 2015, widespread Zika virus outbreaks in Central and South America have caused increases in microcephaly cases, and this acute problem requires urgent attention. We employed molecular dynamics and Gaussian accelerated molecular dynamics techniques to investigate the structure of Zika NS5 prote...

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Detalles Bibliográficos
Autores principales: Chuang, Chih-Hung, Chiou, Shean-jaw, Cheng, Tian-Lu, Wang, Yeng-Tseng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5910437/
https://www.ncbi.nlm.nih.gov/pubmed/29679079
http://dx.doi.org/10.1038/s41598-018-24775-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5910437/
https://www.ncbi.nlm.nih.gov/pubmed/29679079
http://dx.doi.org/10.1038/s41598-018-24775-4

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