Targeting matrix metalloproteinases with novel diazepine substituted cinnamic acid derivatives: design, synthesis, in vitro and in silico studies

Lung cancer is the notable cause of cancer associated deaths worldwide. Recent studies revealed that the expression of matrix metalloproteinases (MMPs) is extremely high in lung tumors compared with non-malignant lung tissue. MMPs (-2 and -9) play an important part in tumor development and angiogene...

Descripción completa

Detalles Bibliográficos
Autores principales: Rathee, Dharmender, Lather, Viney, Grewal, Ajmer Singh, Dureja, Harish
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5910448/
https://www.ncbi.nlm.nih.gov/pubmed/29679218
http://dx.doi.org/10.1186/s13065-018-0411-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5910448/
https://www.ncbi.nlm.nih.gov/pubmed/29679218
http://dx.doi.org/10.1186/s13065-018-0411-8

Ejemplares similares