HIV-1 infection of microglial cells in a reconstituted humanized mouse model and identification of compounds that selectively reverse HIV latency

Most studies of HIV latency focus on the peripheral population of resting memory T cells, but the brain also contains a distinct reservoir of HIV-infected cells in microglia, perivascular macrophages, and astrocytes. Studying HIV in the brain has been challenging, since live cells are difficult to r...

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Detalles Bibliográficos
Autores principales: Llewellyn, George N., Alvarez-Carbonell, David, Chateau, Morgan, Karn, Jonathan, Cannon, Paula M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5910454/
https://www.ncbi.nlm.nih.gov/pubmed/29256041
http://dx.doi.org/10.1007/s13365-017-0604-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5910454/
https://www.ncbi.nlm.nih.gov/pubmed/29256041
http://dx.doi.org/10.1007/s13365-017-0604-2

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