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Downregulation of p53 drives autophagy during human trophoblast differentiation

The placental barrier is crucial for the supply of nutrients and oxygen to the developing fetus and is maintained by differentiation and fusion of mononucleated cytotrophoblasts into the syncytiotrophoblast, a process only partially understood. Here transcriptome and pathway analyses during differen...

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Detalles Bibliográficos
Autores principales: Gauster, Martin, Maninger, Sabine, Siwetz, Monika, Deutsch, Alexander, El-Heliebi, Amin, Kolb-Lenz, Dagmar, Hiden, Ursula, Desoye, Gernot, Herse, Florian, Prokesch, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5910494/
https://www.ncbi.nlm.nih.gov/pubmed/29080089
http://dx.doi.org/10.1007/s00018-017-2695-6