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Gene repression via multiplex gRNA strategy in Y. lipolytica

BACKGROUND: The oleaginous yeast Yarrowia lipolytica is a promising microbial cell factory due to their biochemical characteristics and native capacity to accumulate lipid-based chemicals. To create heterogenous biosynthesis pathway and manipulate metabolic flux in Y. lipolytica, numerous studies ha...

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Detalles Bibliográficos
Autores principales: Zhang, Jin-lai, Peng, Yang-Zi, Liu, Duo, Liu, Hong, Cao, Ying-Xiu, Li, Bing-Zhi, Li, Chun, Yuan, Ying-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5910576/
https://www.ncbi.nlm.nih.gov/pubmed/29678175
http://dx.doi.org/10.1186/s12934-018-0909-8