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Radiosensitization of clioquinol and zinc in human cancer cell lines

BACKGROUND: We previously reported that clioquinol acts as a zinc ionophore and inhibits the NF-κB signalling pathway. Other research has demonstrated that zinc deficiency plays a vital role in the occurrence and development of some solid tumours, and intracellular zinc supplementation may reverse t...

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Detalles Bibliográficos
Autores principales: Lu, Shan, Ke, Yuan, Wu, Chaoyan, Zhong, Yahua, Xie, Conghua, Zhou, Yunfeng, Zhou, Fuxiang, Yu, Haijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5910585/
https://www.ncbi.nlm.nih.gov/pubmed/29678153
http://dx.doi.org/10.1186/s12885-018-4264-2