Glial interleukin-1β upregulates neuronal sodium channel 1.7 in trigeminal ganglion contributing to temporomandibular joint inflammatory hypernociception in rats

BACKGROUND: The proinflammatory cytokine interleukin-1β (IL-1β) drives pain by inducing the expression of inflammatory mediators; however, its ability to regulate sodium channel 1.7 (Nav1.7), a key driver of temporomandibular joint (TMJ) hypernociception, remains unknown. IL-1β induces cyclooxygenas...

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Detalles Bibliográficos
Autores principales: Zhang, Peng, Bi, Rui-Yun, Gan, Ye-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5910598/
https://www.ncbi.nlm.nih.gov/pubmed/29678208
http://dx.doi.org/10.1186/s12974-018-1154-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5910598/
https://www.ncbi.nlm.nih.gov/pubmed/29678208
http://dx.doi.org/10.1186/s12974-018-1154-0

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