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Comparison of normalization methods for the analysis of metagenomic gene abundance data

BACKGROUND: In shotgun metagenomics, microbial communities are studied through direct sequencing of DNA without any prior cultivation. By comparing gene abundances estimated from the generated sequencing reads, functional differences between the communities can be identified. However, gene abundance...

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Detalles Bibliográficos
Autores principales: Pereira, Mariana Buongermino, Wallroth, Mikael, Jonsson, Viktor, Kristiansson, Erik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5910605/
https://www.ncbi.nlm.nih.gov/pubmed/29678163
http://dx.doi.org/10.1186/s12864-018-4637-6