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Comparison of normalization methods for the analysis of metagenomic gene abundance data
BACKGROUND: In shotgun metagenomics, microbial communities are studied through direct sequencing of DNA without any prior cultivation. By comparing gene abundances estimated from the generated sequencing reads, functional differences between the communities can be identified. However, gene abundance...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5910605/ https://www.ncbi.nlm.nih.gov/pubmed/29678163 http://dx.doi.org/10.1186/s12864-018-4637-6 |