Expression of MATE1, P-gp, OCTN1 and OCTN2, in epithelial and immune cells in the lung of COPD and healthy individuals

BACKGROUND: Several inhaled drugs are dependent on organic cation transporters to cross cell membranes. To further evaluate their potential to impact on inhaled drug disposition, the localization of MATE1, P-gp, OCTN1 and OCTN2 were investigated in human lung. METHODS: Transporter proteins were anal...

Descripción completa

Detalles Bibliográficos
Autores principales: Berg, Tove, Hegelund-Myrbäck, Tove, Öckinger, Johan, Zhou, Xiao-Hong, Brännström, Marie, Hagemann-Jensen, Michael, Werkström, Viktoria, Seidegård, Janeric, Grunewald, Johan, Nord, Magnus, Gustavsson, Lena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5910606/
https://www.ncbi.nlm.nih.gov/pubmed/29678179
http://dx.doi.org/10.1186/s12931-018-0760-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5910606/
https://www.ncbi.nlm.nih.gov/pubmed/29678179
http://dx.doi.org/10.1186/s12931-018-0760-9

Ejemplares similares