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Expression of MATE1, P-gp, OCTN1 and OCTN2, in epithelial and immune cells in the lung of COPD and healthy individuals

BACKGROUND: Several inhaled drugs are dependent on organic cation transporters to cross cell membranes. To further evaluate their potential to impact on inhaled drug disposition, the localization of MATE1, P-gp, OCTN1 and OCTN2 were investigated in human lung. METHODS: Transporter proteins were anal...

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Detalles Bibliográficos
Autores principales:	Berg, Tove, Hegelund-Myrbäck, Tove, Öckinger, Johan, Zhou, Xiao-Hong, Brännström, Marie, Hagemann-Jensen, Michael, Werkström, Viktoria, Seidegård, Janeric, Grunewald, Johan, Nord, Magnus, Gustavsson, Lena
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5910606/ https://www.ncbi.nlm.nih.gov/pubmed/29678179 http://dx.doi.org/10.1186/s12931-018-0760-9

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