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Stability of an ophthalmic formulation of polyhexamethylene biguanide in gamma-sterilized and ethylene oxide sterilized low density polyethylene multidose eyedroppers

BACKGROUND: Polyhexamethylene biguanide (PHMB) eye drops are a frequently used medication to treat Acanthamoeba keratitis. In the absence of marketed PHMB eye drops, pharmacy-compounding units are needed to prepare this much needed treatment, but the lack of validated PHMB stability data severely li...

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Detalles Bibliográficos
Autores principales: Bouattour, Yassine, Chennell, Philip, Wasiak, Mathieu, Jouannet, Mireille, Sautou, Valérie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5910790/
https://www.ncbi.nlm.nih.gov/pubmed/29682408
http://dx.doi.org/10.7717/peerj.4549