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Mechanosensitivity of Jagged–Notch signaling can induce a switch-type behavior in vascular homeostasis
Hemodynamic forces and Notch signaling are both known as key regulators of arterial remodeling and homeostasis. However, how these two factors integrate in vascular morphogenesis and homeostasis is unclear. Here, we combined experiments and modeling to evaluate the impact of the integration of mecha...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5910818/ https://www.ncbi.nlm.nih.gov/pubmed/29610298 http://dx.doi.org/10.1073/pnas.1715277115 |