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Ectopic neurogenesis induced by prenatal antiepileptic drug exposure augments seizure susceptibility in adult mice
Epilepsy is a neurological disorder often associated with seizure that affects ∼0.7% of pregnant women. During pregnancy, most epileptic patients are prescribed antiepileptic drugs (AEDs) such as valproic acid (VPA) to control seizure activity. Here, we show that prenatal exposure to VPA in mice inc...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5910824/ https://www.ncbi.nlm.nih.gov/pubmed/29610328 http://dx.doi.org/10.1073/pnas.1716479115 |