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Ectopic neurogenesis induced by prenatal antiepileptic drug exposure augments seizure susceptibility in adult mice

Epilepsy is a neurological disorder often associated with seizure that affects ∼0.7% of pregnant women. During pregnancy, most epileptic patients are prescribed antiepileptic drugs (AEDs) such as valproic acid (VPA) to control seizure activity. Here, we show that prenatal exposure to VPA in mice inc...

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Detalles Bibliográficos
Autores principales: Sakai, Atsuhiko, Matsuda, Taito, Doi, Hiroyoshi, Nagaishi, Yukiko, Kato, Kiyoko, Nakashima, Kinichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5910824/
https://www.ncbi.nlm.nih.gov/pubmed/29610328
http://dx.doi.org/10.1073/pnas.1716479115