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Transient fibrosis resolves via fibroblast inactivation in the regenerating zebrafish heart

In the zebrafish (Danio rerio), regeneration and fibrosis after cardiac injury are not mutually exclusive responses. Upon cardiac cryoinjury, collagen and other extracellular matrix (ECM) proteins accumulate at the injury site. However, in contrast to the situation in mammals, fibrosis is transient...

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Detalles Bibliográficos
Autores principales: Sánchez-Iranzo, Héctor, Galardi-Castilla, María, Sanz-Morejón, Andrés, González-Rosa, Juan Manuel, Costa, Ricardo, Ernst, Alexander, Sainz de Aja, Julio, Langa, Xavier, Mercader, Nadia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5910827/
https://www.ncbi.nlm.nih.gov/pubmed/29610343
http://dx.doi.org/10.1073/pnas.1716713115