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Distinct thermodynamic signature of oligomer generation in the aggregation of the amyloid-β peptide
Mapping energy landscapes has proved to be a powerful tool for studying reaction mechanisms. Many complex biomolecular assembly processes, however, have remained challenging to access using this approach, including the aggregation of peptides and proteins into amyloid fibrils implicated in various d...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5911155/ https://www.ncbi.nlm.nih.gov/pubmed/29581486 http://dx.doi.org/10.1038/s41557-018-0023-x |