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Acute dose of melatonin via Nrf2 dependently prevents acute ethanol-induced neurotoxicity in the developing rodent brain

BACKGROUND: Melatonin is a well-known potent endogenous antioxidant pharmacological agent with significant neuroprotective actions. Here in the current study, we explored the nuclear factor erythroid 2-related factor 2 (Nrf2) gene-dependent antioxidant mechanism underlying the neuroprotective effect...

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Detalles Bibliográficos
Autores principales: Ali, Tahir, Rehman, Shafiq Ur, Shah, Fawad Ali, Kim, Myeong Ok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5911370/
https://www.ncbi.nlm.nih.gov/pubmed/29679979
http://dx.doi.org/10.1186/s12974-018-1157-x