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Clec9a-Mediated Ablation of Conventional Dendritic Cells Suggests a Lymphoid Path to Generating Dendritic Cells In Vivo

Conventional dendritic cells (cDCs) are versatile activators of immune responses that develop as part of the myeloid lineage downstream of hematopoietic stem cells. We have recently shown that in mice precursors of cDCs, but not of other leukocytes, are marked by expression of DNGR-1/CLEC9A. To gene...

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Detalles Bibliográficos
Autores principales: Salvermoser, Johanna, van Blijswijk, Janneke, Papaioannou, Nikos E., Rambichler, Stephan, Pasztoi, Maria, Pakalniškytė, Dalia, Rogers, Neil C., Keppler, Selina J., Straub, Tobias, Reis e Sousa, Caetano, Schraml, Barbara U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5911463/
https://www.ncbi.nlm.nih.gov/pubmed/29713321
http://dx.doi.org/10.3389/fimmu.2018.00699