Astragaloside IV Inhibits Triglyceride Accumulation in Insulin-Resistant HepG2 Cells via AMPK-Induced SREBP-1c Phosphorylation

Objective: Insulin resistance (IR) is a risk factor for non-alcoholic fatty liver disease (NAFLD), which is characterized by lipid accumulation in hepatocytes. AMP-activated protein kinase (AMPK)-induced sterol regulatory element binding protein-1c (SREBP-1c) phosphorylation is crucial for proper re...

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Detalles Bibliográficos
Autores principales: Wang, Chunyi, Li, Yan, Hao, Mengjiao, Li, Weimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5911465/
https://www.ncbi.nlm.nih.gov/pubmed/29713279
http://dx.doi.org/10.3389/fphar.2018.00345

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5911465/
https://www.ncbi.nlm.nih.gov/pubmed/29713279
http://dx.doi.org/10.3389/fphar.2018.00345

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