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TCR Signaling Abnormalities in Human Th2-Associated Atopic Disease
Stimulation of naïve CD4 T cells with weak T cell receptor agonists even in the absence of T helper-skewing cytokines can result in IL-4 production which can drive a Th2 response. Evidence for the in vivo consequences of such a phenomenon can be found in a number of mouse models and, importantly, a...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5911486/ https://www.ncbi.nlm.nih.gov/pubmed/29713322 http://dx.doi.org/10.3389/fimmu.2018.00719 |