Amino-Terminal Processing of Helicobacter pylori Serine Protease HtrA: Role in Oligomerization and Activity Regulation

The HtrA family of serine proteases is found in most bacteria, and plays an essential role in the virulence of the gastric pathogen Helicobacter pylori. Secreted H. pylori HtrA (HtrA(Hp)) cleaves various junctional proteins such as E-cadherin disrupting the epithelial barrier, which is crucial for b...

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Detalles Bibliográficos
Autores principales: Albrecht, Nicole, Tegtmeyer, Nicole, Sticht, Heinrich, Skórko-Glonek, Joanna, Backert, Steffen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5911493/
https://www.ncbi.nlm.nih.gov/pubmed/29713313
http://dx.doi.org/10.3389/fmicb.2018.00642

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5911493/
https://www.ncbi.nlm.nih.gov/pubmed/29713313
http://dx.doi.org/10.3389/fmicb.2018.00642

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