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Epigenetic silencing of RNF144A expression in breast cancer cells through promoter hypermethylation and MBD4

Emerging evidence shows that ring finger protein 144A (RNF144A), a poorly characterized member of the Ring‐between‐Ring (RBR) family of E3 ubiquitin ligases, is a potential tumor suppressor gene. However, its regulatory mechanism in breast cancer remains undefined. Here, we report that RNF144A promo...

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Detalles Bibliográficos
Autores principales: Zhang, Ye, Yang, Yin‐Long, Zhang, Fang‐Lin, Liao, Xiao‐Hong, Shao, Zhi‐Min, Li, Da‐Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5911569/
https://www.ncbi.nlm.nih.gov/pubmed/29473320
http://dx.doi.org/10.1002/cam4.1324