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Chemotherapy and terminal skeletal muscle differentiation in WT1‐mutant Wilms tumors

Wilms tumors (WT) with WT1 mutations do not respond well to preoperative chemotherapy by volume reduction, suggesting resistance to chemotherapy. The histologic pattern of this tumor subtype indicates an intrinsic mesenchymal differentiation potential. Currently, it is unknown whether cytotoxic trea...

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Detalles Bibliográficos
Autores principales: Royer‐Pokora, Brigitte, Beier, Manfred, Brandt, Artur, Duhme, Constanze, Busch, Maike, de Torres, Carmen, Royer, Hans‐Dieter, Mora, Jaume
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5911586/
https://www.ncbi.nlm.nih.gov/pubmed/29542868
http://dx.doi.org/10.1002/cam4.1379