Cargando…
Chemotherapy and terminal skeletal muscle differentiation in WT1‐mutant Wilms tumors
Wilms tumors (WT) with WT1 mutations do not respond well to preoperative chemotherapy by volume reduction, suggesting resistance to chemotherapy. The histologic pattern of this tumor subtype indicates an intrinsic mesenchymal differentiation potential. Currently, it is unknown whether cytotoxic trea...
Autores principales: | Royer‐Pokora, Brigitte, Beier, Manfred, Brandt, Artur, Duhme, Constanze, Busch, Maike, de Torres, Carmen, Royer, Hans‐Dieter, Mora, Jaume |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5911586/ https://www.ncbi.nlm.nih.gov/pubmed/29542868 http://dx.doi.org/10.1002/cam4.1379 |
Ejemplares similares
-
Comprehensive Biology and Genetics Compendium of Wilms Tumor Cell Lines with Different WT1 Mutations
por: Royer-Pokora, Brigitte, et al.
Publicado: (2020) -
Classification of a frameshift/extended and a stop mutation in WT1 as gain-of-function mutations that activate cell cycle genes and promote Wilms tumour cell proliferation
por: Busch, Maike, et al.
Publicado: (2014) -
Gene expression studies of WT1 mutant Wilms tumor cell lines in the frame work of published kidney development data reveals their early kidney stem cell origin
por: Royer-Pokora, Brigitte, et al.
Publicado: (2023) -
Establishment of a Conditionally Immortalized Wilms Tumor Cell Line with a Homozygous WT1 Deletion within a Heterozygous 11p13 Deletion and UPD Limited to 11p15
por: Brandt, Artur, et al.
Publicado: (2016) -
Evidence for susceptibility genes to familial Wilms tumour in addition to WT1, FWT1 and FWT2
por: Rapley, E A, et al.
Publicado: (2000)