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Nutlin‐3a as a novel anticancer agent for adrenocortical carcinoma with CTNNB1 mutation

Adrenocortical carcinoma (ACC) is a rare malignancy, and CTNNB1 is frequently mutated in ACC. Our study aims to screen for effective agents with antineoplastic activity against ACC with CTNNB1 mutation. In‐silico screening of the Genomics of Drug Sensitivity in Cancer (GDSC) database was conducted....

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Detalles Bibliográficos
Autores principales: Hui, Wen, Liu, Shenghua, Zheng, Jie, Fang, Zujun, Ding, Qiang, Feng, Chenchen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5911589/
https://www.ncbi.nlm.nih.gov/pubmed/29532999
http://dx.doi.org/10.1002/cam4.1431