Inhibition of PC4 radiosensitizes non‐small cell lung cancer by transcriptionally suppressing XLF

Positive cofactor 4 (PC4) participates in DNA damage repair and involved in nonhomologous end joining (NHEJ). Our previous results demonstrated that knockdown of PC4 downregulated the expression of XRCC4‐like factor (XLF) in esophageal squamous cell carcinoma. However, the mechanism how PC4 regulate...

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Detalles Bibliográficos
Autores principales: Zhang, Tian, Liu, Xiaojie, Chen, Xiuli, Wang, Jing, Wang, Yuwen, Qian, Dong, Pang, Qingsong, Wang, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5911594/
https://www.ncbi.nlm.nih.gov/pubmed/29522271
http://dx.doi.org/10.1002/cam4.1332

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5911594/
https://www.ncbi.nlm.nih.gov/pubmed/29522271
http://dx.doi.org/10.1002/cam4.1332

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