Direct and cytokine‐mediated effects of albumin‐fused growth hormone, TV‐1106, on CYP enzyme expression in human hepatocytes in vitro

Some biologics can modulate cytokines that may lead to changes in expression of drug‐metabolizing enzymes and cause drug‐drug interactions (DDI). DDI potential of TV‐1106—an albumin‐fused growth hormone (GH)—was investigated. In this study, human blood was exposed to recombinant human growth hormone...

Descripción completa

Detalles Bibliográficos
Autores principales: Czerwiński, Maciej, Amunom, Immaculate, Piryatinsky, Victor, Hallak, Hussein, Sahly, Yousif, Bar‐Ilan, Oren, Bolliger, Paul, Bassan, Merav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5911691/
https://www.ncbi.nlm.nih.gov/pubmed/29721322
http://dx.doi.org/10.1002/prp2.397

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5911691/
https://www.ncbi.nlm.nih.gov/pubmed/29721322
http://dx.doi.org/10.1002/prp2.397

Ejemplares similares