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A DNA-conjugated small molecule catalyst enzyme mimic for site-selective ester hydrolysis

The challenge of site-selectivity must be overcome in many chemical research contexts, including selective functionalization in complex natural products and labeling of one biomolecule in a living system. Synthetic catalysts incorporating molecular recognition domains can mimic naturally-occurring e...

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Detalles Bibliográficos
Autores principales: Flanagan, Moira L., Arguello, A. Emilia, Colman, Drew E., Kim, Jiyeon, Krejci, Jesse N., Liu, Shimu, Yao, Yueyu, Zhang, Yu, Gorin, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5911826/
https://www.ncbi.nlm.nih.gov/pubmed/29732115
http://dx.doi.org/10.1039/c7sc04554a