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A DNA-conjugated small molecule catalyst enzyme mimic for site-selective ester hydrolysis
The challenge of site-selectivity must be overcome in many chemical research contexts, including selective functionalization in complex natural products and labeling of one biomolecule in a living system. Synthetic catalysts incorporating molecular recognition domains can mimic naturally-occurring e...
Autores principales: | Flanagan, Moira L., Arguello, A. Emilia, Colman, Drew E., Kim, Jiyeon, Krejci, Jesse N., Liu, Shimu, Yao, Yueyu, Zhang, Yu, Gorin, David J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Royal Society of Chemistry
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5911826/ https://www.ncbi.nlm.nih.gov/pubmed/29732115 http://dx.doi.org/10.1039/c7sc04554a |
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