Microcrystalline Tyrosine and Aluminum as Adjuvants in Allergen-Specific Immunotherapy Protect from IgE-Mediated Reactivity in Mouse Models and Act Independently of Inflammasome and TLR Signaling

Allergen immunotherapy (AIT) is the only modality that can modify immune responses to allergen exposure, but therapeutic coverage is low. One strategy to improve AIT safety and efficacy is the use of new or improved adjuvants. This study investigates immune responses produced by microcrystalline tyr...

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Detalles Bibliográficos
Autores principales: Leuthard, Deborah S., Duda, Agathe, Freiberger, Sandra N., Weiss, Sina, Dommann, Isabella, Fenini, Gabriele, Contassot, Emmanuel, Kramer, Matthias F., Skinner, Murray A., Kündig, Thomas M., Heath, Matthew D., Johansen, Pål
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AAI 2018
Materias:
Immunotherapy and Vaccines
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5911931/
https://www.ncbi.nlm.nih.gov/pubmed/29592962
http://dx.doi.org/10.4049/jimmunol.1800035

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5911931/
https://www.ncbi.nlm.nih.gov/pubmed/29592962
http://dx.doi.org/10.4049/jimmunol.1800035

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