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Role of BMI1 in epithelial ovarian cancer: investigated via the CRISPR/Cas9 system and RNA sequencing

BACKGROUND: B-cell-specific Moloney murine leukemia virus integration site 1 (BMI1) might be an appropriate biomarker in the management of epithelial ovarian cancer (EOC). However, the biological role of BMI1 and its relevant molecular mechanism needs further elaboration. Clustered regularly intersp...

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Detalles Bibliográficos
Autores principales: Zhao, Qianying, Qian, Qiuhong, Cao, Dongyan, Yang, Jiaxin, Gui, Ting, Shen, Keng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5911954/
https://www.ncbi.nlm.nih.gov/pubmed/29685168
http://dx.doi.org/10.1186/s13048-018-0406-z