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Brain vascular heterogeneity: implications for disease pathogenesis and design of in vitro blood–brain barrier models

The vertebrate blood–brain barrier (BBB) is composed of cerebral microvascular endothelial cells (CEC). The BBB acts as a semi-permeable cellular interface that tightly regulates bidirectional molecular transport between blood and the brain parenchyma in order to maintain cerebral homeostasis. The C...

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Detalles Bibliográficos
Autores principales: Noumbissi, Midrelle E., Galasso, Bianca, Stins, Monique F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5911972/
https://www.ncbi.nlm.nih.gov/pubmed/29688865
http://dx.doi.org/10.1186/s12987-018-0097-2