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Brain vascular heterogeneity: implications for disease pathogenesis and design of in vitro blood–brain barrier models
The vertebrate blood–brain barrier (BBB) is composed of cerebral microvascular endothelial cells (CEC). The BBB acts as a semi-permeable cellular interface that tightly regulates bidirectional molecular transport between blood and the brain parenchyma in order to maintain cerebral homeostasis. The C...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5911972/ https://www.ncbi.nlm.nih.gov/pubmed/29688865 http://dx.doi.org/10.1186/s12987-018-0097-2 |