Nickel-catalyzed enantioselective allylic alkylation of lactones and lactams with unactivated allylic alcohols

The first nickel-catalyzed enantioselective allylic alkylation of lactone and lactam substrates to deliver products bearing an all-carbon quaternary stereocenter is reported. The reaction, which utilizes a commercially available chiral bisphosphine ligand, proceeds in good yield with a high level of...

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Detalles Bibliográficos
Autores principales: Ngamnithiporn, Aurapat, Jette, Carina I., Bachman, Shoshana, Virgil, Scott C., Stoltz, Brian M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5912103/
https://www.ncbi.nlm.nih.gov/pubmed/29732133
http://dx.doi.org/10.1039/c7sc05216b

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5912103/
https://www.ncbi.nlm.nih.gov/pubmed/29732133
http://dx.doi.org/10.1039/c7sc05216b

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