Inhibition of ghrelin o-acyltransferase attenuated lipotoxicity by inducing autophagy via AMPK–mTOR pathway

BACKGROUND: Nonalcoholic fatty liver disease (NAFLD) has been considered the most commonly occurring chronic hepatopathy in the world. Ghrelin o-acyltransferase (GOAT) is an acylation enzyme which has an acylated position 3 serine on ghrelin. Recent investigation revealed that activated autophagy co...

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Detalles Bibliográficos
Autores principales: Zhang, Shaoren, Mao, Yuqing, Fan, Xiaoming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5912383/
https://www.ncbi.nlm.nih.gov/pubmed/29713145
http://dx.doi.org/10.2147/DDDT.S158985

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5912383/
https://www.ncbi.nlm.nih.gov/pubmed/29713145
http://dx.doi.org/10.2147/DDDT.S158985

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