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In vivo insertion pool sequencing identifies virulence factors in a complex fungal–host interaction

Large-scale insertional mutagenesis screens can be powerful genome-wide tools if they are streamlined with efficient downstream analysis, which is a serious bottleneck in complex biological systems. A major impediment to the success of next-generation sequencing (NGS)-based screens for virulence fac...

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Detalles Bibliográficos
Autores principales: Uhse, Simon, Pflug, Florian G., Stirnberg, Alexandra, Ehrlinger, Klaus, von Haeseler, Arndt, Djamei, Armin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5912717/
https://www.ncbi.nlm.nih.gov/pubmed/29684023
http://dx.doi.org/10.1371/journal.pbio.2005129