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In vivo insertion pool sequencing identifies virulence factors in a complex fungal–host interaction
Large-scale insertional mutagenesis screens can be powerful genome-wide tools if they are streamlined with efficient downstream analysis, which is a serious bottleneck in complex biological systems. A major impediment to the success of next-generation sequencing (NGS)-based screens for virulence fac...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5912717/ https://www.ncbi.nlm.nih.gov/pubmed/29684023 http://dx.doi.org/10.1371/journal.pbio.2005129 |