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Development and validation of brain target controlled infusion of propofol in mice

Mechanisms through which anesthetics disrupt neuronal activity are incompletely understood. In order to study anesthetic mechanisms in the intact brain, tight control over anesthetic pharmacology in a genetically and neurophysiologically accessible animal model is essential. Here, we developed a pha...

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Detalles Bibliográficos
Autores principales: Shortal, Brenna P., Reitz, Sarah L., Aggarwal, Adeeti, Meng, Qing C., McKinstry-Wu, Andrew R., Kelz, Max B., Proekt, Alex
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5912730/
https://www.ncbi.nlm.nih.gov/pubmed/29684039
http://dx.doi.org/10.1371/journal.pone.0194949