CD44-mediated hyaluronan binding marks proliferating hematopoietic progenitor cells and promotes bone marrow engraftment

CD44 is a widely expressed cell adhesion molecule that binds to the extracellular matrix component, hyaluronan. However, this interaction is not constitutive in most immune cells at steady state, as the ability of CD44 to engage hyaluronan is highly regulated. While activated T cells and macrophages...

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Detalles Bibliográficos
Autores principales: Lee-Sayer, Sally S. M., Dougan, Meghan N., Cooper, Jesse, Sanderson, Leslie, Dosanjh, Manisha, Maxwell, Christopher A., Johnson, Pauline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5912764/
https://www.ncbi.nlm.nih.gov/pubmed/29684048
http://dx.doi.org/10.1371/journal.pone.0196011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5912764/
https://www.ncbi.nlm.nih.gov/pubmed/29684048
http://dx.doi.org/10.1371/journal.pone.0196011

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