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CD44-mediated hyaluronan binding marks proliferating hematopoietic progenitor cells and promotes bone marrow engraftment
CD44 is a widely expressed cell adhesion molecule that binds to the extracellular matrix component, hyaluronan. However, this interaction is not constitutive in most immune cells at steady state, as the ability of CD44 to engage hyaluronan is highly regulated. While activated T cells and macrophages...
Autores principales: | Lee-Sayer, Sally S. M., Dougan, Meghan N., Cooper, Jesse, Sanderson, Leslie, Dosanjh, Manisha, Maxwell, Christopher A., Johnson, Pauline |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5912764/ https://www.ncbi.nlm.nih.gov/pubmed/29684048 http://dx.doi.org/10.1371/journal.pone.0196011 |
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