Pharmacological analysis of zebrafish lphn3.1 morphant larvae suggests that saturated dopaminergic signaling could underlie the ADHD-like locomotor hyperactivity

Polymorphisms in the gene coding for the adhesion G-protein coupled receptor LPHN3 are a risk factor for attention-deficit/hyperactivity disorder (ADHD). Transient down-regulation of latrophilin3.1 (lphn3.1), the zebrafish LPHN3 homologue, causes hyperactivity. Zebrafish injected with a lphn3.1-spec...

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Detalles Bibliográficos
Autores principales: Lange, Merlin, Froc, Cynthia, Grunwald, Hannah, Norton, William H.J., Bally-Cuif, Laure
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pergamon Press 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5912797/
https://www.ncbi.nlm.nih.gov/pubmed/29496512
http://dx.doi.org/10.1016/j.pnpbp.2018.02.010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5912797/
https://www.ncbi.nlm.nih.gov/pubmed/29496512
http://dx.doi.org/10.1016/j.pnpbp.2018.02.010

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