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The ISG15 Conjugation System
ISG15 is a ubiquitin-like modifier that is expressed in response to type 1 interferon signaling (IFN-α/β) and plays a role in antiviral responses. The core E1, E2, and E3 enzymes for ISG15 are Ube1L, UbcH8, and Herc5, respectively, and these are all also induced at the transcriptional level by IFN-α...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5912894/ https://www.ncbi.nlm.nih.gov/pubmed/22350882 http://dx.doi.org/10.1007/978-1-61779-474-2_9 |