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A cAMP/PKA/Kinesin-1 Axis Promotes the Axonal Transport of Mitochondria in Aging Drosophila Neurons

Mitochondria play fundamental roles within cells, including energy provision, calcium homeostasis, and the regulation of apoptosis. The transport of mitochondria by microtubule-based motors is critical for neuronal structure and function. This process allows local requirements for mitochondrial func...

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Detalles Bibliográficos
Autores principales: Vagnoni, Alessio, Bullock, Simon L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5912900/
https://www.ncbi.nlm.nih.gov/pubmed/29606421
http://dx.doi.org/10.1016/j.cub.2018.02.048