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A novel assay provides sensitive measurement of physiologically relevant changes in albumin permeability in isolated human and rodent glomeruli

Increased urinary albumin excretion is a key feature of glomerular disease but has limitations as a measure of glomerular permeability. Here we describe a novel assay to measure the apparent albumin permeability of single capillaries in glomeruli, isolated from perfused kidneys cleared of red blood...

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Detalles Bibliográficos
Autores principales: Desideri, Sara, Onions, Karen L., Qiu, Yan, Ramnath, Raina D., Butler, Matthew J., Neal, Christopher R., King, Matthew L.R., Salmon, Andrew E., Saleem, Moin A., Welsh, Gavin I., Michel, C. Charles, Satchell, Simon C., Salmon, Andrew H.J., Foster, Rebecca R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5912930/
https://www.ncbi.nlm.nih.gov/pubmed/29433915
http://dx.doi.org/10.1016/j.kint.2017.12.003