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The deubiquitinating enzyme UCHL1 negatively regulates the immunosuppressive capacity and survival of multipotent mesenchymal stromal cells

It is known that proinflammatory cytokines empower multipotent mesenchymal stromal cells (MSCs) the immunosuppressive capacity to treat various inflammatory diseases. Nevertheless, how the proinflammatory cytokines modulate the immunosuppressive capacity of MSCs is poorly understood. In the present...

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Detalles Bibliográficos
Autores principales: Gu, Yuting, Ding, Xinyuan, Huang, Jiefang, Xue, Mingxing, Zhang, Jie, Wang, Qiwei, Yu, Hongshuang, Wang, Yanan, Zhao, Fang, Wang, Hui, Jin, Min, Wu, Yeming, Zhang, Yanyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5913136/
https://www.ncbi.nlm.nih.gov/pubmed/29686406
http://dx.doi.org/10.1038/s41419-018-0532-y