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Zika virus propagation and release in human fetal astrocytes can be suppressed by neutral sphingomyelinase-2 inhibitor GW4869

Zika virus (ZIKV) is a neurotrophic flavivirus that is capable of infecting humans, leading to brain abnormalities during fetal development. The ZIKV infectivity in neural target cells remains poorly understood. Here, we found that ZIKV specifically infected glial fibrillary acidic protein- and S100...

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Detalles Bibliográficos
Autores principales: Huang, Yunlong, Li, Yuju, Zhang, Hainan, Zhao, Runze, Jing, Ran, Xu, Yinghua, He, Miao, Peer, Justin, Kim, Yeong C., Luo, Jiangtao, Tong, Zenghan, Zheng, Jialin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5913238/
https://www.ncbi.nlm.nih.gov/pubmed/29707233
http://dx.doi.org/10.1038/s41421-018-0017-2