Mangiferin Enhanced Autophagy via Inhibiting mTORC1 Pathway to Prevent High Glucose-Induced Cardiomyocyte Injury

Mangiferin functions as a perfect anti-oxidative compound in the diabetic heart, however, the exact mechanism remains to be elucidated. Here, we show the cardioprotective effect of mangiferin under high glucose-induced cardiotoxic condition mainly contributed to enhanced autophagy via suppressing mT...

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Detalles Bibliográficos
Autores principales: Hou, Jun, Zheng, Dezhi, Xiao, Wenjing, Li, Dandan, Ma, Jie, Hu, Yonghe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5913280/
https://www.ncbi.nlm.nih.gov/pubmed/29719509
http://dx.doi.org/10.3389/fphar.2018.00383

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5913280/
https://www.ncbi.nlm.nih.gov/pubmed/29719509
http://dx.doi.org/10.3389/fphar.2018.00383

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