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Mangiferin Enhanced Autophagy via Inhibiting mTORC1 Pathway to Prevent High Glucose-Induced Cardiomyocyte Injury
Mangiferin functions as a perfect anti-oxidative compound in the diabetic heart, however, the exact mechanism remains to be elucidated. Here, we show the cardioprotective effect of mangiferin under high glucose-induced cardiotoxic condition mainly contributed to enhanced autophagy via suppressing mT...
Autores principales: | Hou, Jun, Zheng, Dezhi, Xiao, Wenjing, Li, Dandan, Ma, Jie, Hu, Yonghe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5913280/ https://www.ncbi.nlm.nih.gov/pubmed/29719509 http://dx.doi.org/10.3389/fphar.2018.00383 |
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