Lysosomal damage after spinal cord injury causes accumulation of RIPK1 and RIPK3 proteins and potentiation of necroptosis

Necroptosis, a regulated necrosis pathway mediated by the receptor-interacting protein kinases 1 and 3 (RIPK1 and RIPK3), is induced following spinal cord injury (SCI) and thought to contribute to neuronal and glial cell death. However, mechanisms leading to activation of necroptosis after SCI remai...

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Detalles Bibliográficos
Autores principales: Liu, Shuo, Li, Yun, Choi, Harry M. C., Sarkar, Chinmoy, Koh, Eugene Y., Wu, Junfang, Lipinski, Marta M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5913300/
https://www.ncbi.nlm.nih.gov/pubmed/29686269
http://dx.doi.org/10.1038/s41419-018-0469-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5913300/
https://www.ncbi.nlm.nih.gov/pubmed/29686269
http://dx.doi.org/10.1038/s41419-018-0469-1

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