Cargando…

Lysosomal damage after spinal cord injury causes accumulation of RIPK1 and RIPK3 proteins and potentiation of necroptosis

Necroptosis, a regulated necrosis pathway mediated by the receptor-interacting protein kinases 1 and 3 (RIPK1 and RIPK3), is induced following spinal cord injury (SCI) and thought to contribute to neuronal and glial cell death. However, mechanisms leading to activation of necroptosis after SCI remai...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Shuo, Li, Yun, Choi, Harry M. C., Sarkar, Chinmoy, Koh, Eugene Y., Wu, Junfang, Lipinski, Marta M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5913300/
https://www.ncbi.nlm.nih.gov/pubmed/29686269
http://dx.doi.org/10.1038/s41419-018-0469-1

Ejemplares similares