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Multi-faceted immunomodulatory and tissue-tropic clinical bacterial isolate potentiates prostate cancer immunotherapy

Immune checkpoint inhibitors have not been effective for immunologically “cold” tumors, such as prostate cancer, which contain scarce tumor infiltrating lymphocytes. We hypothesized that select tissue-specific and immunostimulatory bacteria can potentiate these immunotherapies. Here we show that a p...

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Detalles Bibliográficos
Autores principales: Anker, Jonathan F., Naseem, Anum F., Mok, Hanlin, Schaeffer, Anthony J., Abdulkadir, Sarki A., Thumbikat, Praveen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5913311/
https://www.ncbi.nlm.nih.gov/pubmed/29686284
http://dx.doi.org/10.1038/s41467-018-03900-x