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Multi-faceted immunomodulatory and tissue-tropic clinical bacterial isolate potentiates prostate cancer immunotherapy
Immune checkpoint inhibitors have not been effective for immunologically “cold” tumors, such as prostate cancer, which contain scarce tumor infiltrating lymphocytes. We hypothesized that select tissue-specific and immunostimulatory bacteria can potentiate these immunotherapies. Here we show that a p...
Autores principales: | Anker, Jonathan F., Naseem, Anum F., Mok, Hanlin, Schaeffer, Anthony J., Abdulkadir, Sarki A., Thumbikat, Praveen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5913311/ https://www.ncbi.nlm.nih.gov/pubmed/29686284 http://dx.doi.org/10.1038/s41467-018-03900-x |
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